Biology | Multiple Choice Quiz (2024)

1

Nucleosomes inhibitA)activatorsB)RNA polymeraseC)translationD)assembly of transcription factors

2

Unlike prokaryotes, the control of transcription by eukaryotes is designed to react to change byA)changingB)ignoring changeC)remaining constantD)changing the environment

3

A form of binding motif containing a nearly identical sequence of 60 amino acids in many eukaryotes is theA)homeodomain motifB)zinc finger motifC)leucine zipper motifD)universal motif

4

Which of the following does not occur in the function of the catabolite activator protein (CAP) of E. coli?A)Cyclic-AMP binds to the CAP protein.B)The protein changes shape.C)Space is increased by the binding of tryptophan.D)Helix-turn-helix motifs are enabled to bind to the DNA.

5

All of the following can be found in a human transcription complex exceptA)activatorB)RNAC)enhancerD)silencer

6

Enhancers areA)proteins located adjacent to promotersB)distant sites where regulatory proteins bindC)expediters of RNA polymerase captureD)proteins that bind with repressors, deactivating themE)a bacterial form of promoters

7

When tryptophan is present in the medium, the transcription of tryptophan producing genes in E. coli is stopped by a helix-turn-helix regulator binding to theA)trp repressorB)trp operonC)trp promoterD)trp operatorE)trp polymerase

8

When a homeodomain binds to DNA, the actual binding portion of the homeodomain isA)a leucine zipperB)the operonC)zinc fingersD)the histineE)a helix-turn-helix motif

9

The assembly of transcription factors on a promoter begins some 25 nucleotides upstream where it binds to a start _______________ sequence.A)ATATB)AATTC)TTAAD)TAATE)TATA

10

When tryptophan is present in the environment of E. coli, the tryptophan binds to theA)trp operonB)trp promoterC)trp operatorD)trp repressorE)trp polymerase

11

Transcription factors appear to be unable to bind to a nucleosome becauseA)activators are inhibited by the configurationB)of inhibition of RNA polymeraseC)of histones positioned over promotersD)nucleosomes are especially vulnerable to repressorsE)operators are placed in an inaccessible position

12

In the zinc fingers motif, the spacing of the helical segments is performed byA)beta sheetsB)helical clustersC)zinc atomsD)gamma helicesE)an alpha helix

13

Translation repressor proteins may shut down translation of processed mRNA transcripts byA)binding with the poly-A tailB)resetting the reading frameC)reinserting introns into the transcriptD)excising a short sequence of nucleotides

14

In many animals, the genes that regulate the development of stem cells are activatedA)onceB)only twiceC)up to 10 timesD)over a hundred timesE)not at all

15

The leucine zipper motif involves the cooperation of two _______________ subunits.A)leucineB)proteinC)RNAD)polymeraseE)histone

16

Regulatory domains of most activators interact withA)the transcription factor complexB)RNA polymeraseC)repressorsD)the regulatory factor complexE)the DNA binding domain

17

The operon that controls tryptophan producing genes in E. coli consists of _______________ .A)only one geneB)two genesC)three genesD)four genesE)five genes

18

In order for a gene to be transcribed, RNA polymerase must have access to the DNA helix and be able to bind to the genesA)activatorB)regulatorC)promoterD)operatorE)repressor

19

In the function of the lac operon in E. coli, the lac genes are transcribed in the presence of lactose becauseA)RNA polymerase binds to the operatorB)the repressor cannot bind to the promoterC)an isomer of lactose binds to the repressorD)CAP does not bind to the operatorE)of the absence of cAMP

20

The role of methylation of DNA is now viewed asA)interfering with DNA transcription by blocking base pairing between cytosine and guanineB)complexing with enhancers to prevent transcriptionC)prevention of mutationD)insuring that genes that are turned off, stay offE)irrelevant to gene transcription

21

In order for the helix-turn-helix motif to bind to DNA, the _______________ must fit into the major groove of the DNA.A)homeotic switchesB)zinc fingersC)operatorD)recognition helixE)protein link

22

The most common form of gene expression regulation in both bacteria and eukaryotes isA)translational controlB)transcriptional controlC)post-transcriptional controlD)post-translational controlE)control of passage from the nucleus

23

In eukaryotes, many genes may have to interact with each other, requiring more interacting elements than can fit around a single promoter. This physical limitation is overcome byA)alternating promoters and operatorsB)placing promoters on both sides of each geneC)the use of very long promotersD)distant sites in a chromosome controlling transcription of a geneE)having factors on one chromosome control genes on another gene

24

E. coli is able to use foods other than glucose in the absence of available glucose, because falling levels of glucose cause an increase ofA)cAMPB)CAPC)lactaseD)glu operonsE)tRNA

25

In the absence of glucose, E. coli can import lactose to change into glucose and galactose because CAP binds to theA)cAMPB)DNAC)lac operonD)operatorE)repressor

26

Which is not part of the lac operon?A)repressorB)activator proteinC)operatorD)promotorE)structural gene

27

In an operon the location of the regulatory region occurs ________ the structural genes.A)afterB)withinC)before

28

In eukaryotic gene regulation, the location of the promoter is always before and the location of the enhancer always after the gene being regulated.A)TrueB)False

29

Proteins that block the passage of RNA polymerase are called:A)operonsB)activatorsC)repressorsD)enhancersE)promoters

30

Which of the following is part of an operon?A)structural genesB)an operatorC)a promoterD)a CAP binding siteE)all of the above

31

Which of the following are not matched correctly?A)exon splicing-occurs in nucleusB)post-translational modifications-phosphorylationC)snRNA-splice out exons from transcriptD)activated enhancers-trigger transcriptionE)all are matched correctly

32

A single gene may use a regulatory site to control the expression of that gene, but genes rarely have multiple regulatory sites.A)TrueB)False